GO:0003810 molecular_function protein-glutamine gamma-glutamyltransferase activity
| PAG Title | GO:0003810 molecular_function protein-glutamine gamma-glutamyltransferase activity |
| PAG ID | TAX014794 |
| Type | A |
| Source Link |  GOA |
| Publication Reference | NA |
| PAG Description | Catalysis of the reaction: protein glutamine + alkylamine = protein N5-alkylglutamine + NH3. This reaction is the formation of the N6-(L-isoglutamyl)-L-lysine isopeptide, resulting in cross-linking polypeptide chains; the gamma-carboxamide groups of peptidyl-glutamine residues act as acyl donors, and the 6-amino-groups of peptidyl-lysine residues act as acceptors, to give intra- and intermolecular N6-(5-glutamyl)lysine cross-links. |
| Species | Homo sapiens |
| nCoCo Score | 356 |
| Base PAG ID | TAX014794 |
| Human Phenotyte Annotation | |
| Curator | PAGER curation team |
| Curator Contact | PAGER-contact@googlegroups.com |
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